ncRNA name | TUG1 |
ncRNA Category | lncRNA |
ID | 55000 |
Ensembl | ENSG00000253352 |
Synonyms | TI-227H; LINC00080; NCRNA00080 |
Disease name | cataract |
Species | Homo sapiens |
Tissues/Cell_line | anterior lens capsules; human lens epithelial cell line SRA01/04 |
Methods | transfection, luciferase reporter assay, flow cytometry, qRT-PCR, Western blot, immunoprecipitation |
Expression pattern | up-regulated |
Functional description | TUG1 modulated lens epithelial cell apoptosis through miR-421/caspase-3 axis. |
PubMed ID | 28392351 |
Year | 2017 |
Title | TUG1 promotes lens epithelial cell apoptosis by regulating miR-421/caspase-3 axis in age-related cataract. |
Drug-related ncRNA | NO |
Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.