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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of cataract
ncRNA name TUG1
ncRNA Category lncRNA
ID 55000
Ensembl ENSG00000253352
Synonyms TI-227H; LINC00080; NCRNA00080
Disease name cataract
Species Homo sapiens
Tissues/Cell_line anterior lens capsules; human lens epithelial cell line SRA01/04
Methods transfection, luciferase reporter assay, flow cytometry, qRT-PCR, Western blot, immunoprecipitation
Expression pattern up-regulated
Functional description TUG1 modulated lens epithelial cell apoptosis through miR-421/caspase-3 axis.
PubMed ID 28392351
Year 2017
Title TUG1 promotes lens epithelial cell apoptosis by regulating miR-421/caspase-3 axis in age-related cataract.
Drug-related ncRNA NO

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